Red cells in additive solution |
300 - 350 ml of RBCs in additive solution collected from 450 ml of whole blood |
Sympto- matic anaemia acute or chronic for restoration of O 2 carrying capacity |
1 unit RBC increases Hct 3%, increases Hb by 1gm% (approx.) |
Must be ABO & Rh compatible and X- match compatible |
* Deficiency anaemias treatable pharmaco- logically
* Coagula- tion factor deficiencies |
42 days |
2 o C - 6 o C |
Washed RBCs |
300 - 350 ml red cells washed in NS thrice under Laminar air flow |
Sympto- matic anaemia with Plasma protein antibodies, IgA Ab.s, PNH, H/O febrile reactions |
1 unit RBC increases Hct 3%, increases Hb by 1gm% (approx.) |
Must be ABO & Rh compatible and X- match compatible |
* Deficiency anaemias treatable pharmaco- logically
* Coagula- tion factor deficiencies |
24 hrs, however, to be consumed preferably in 6 hrs |
2 o C - 6 o C |
Fresh frozen Plasma |
200 - 250 ml, prepared within 6 hrs of whole blood collection preserving all clotting factors including labile factors (V & VIII) |
/Multiple coagulation factor deficiency, Massive transfusion, Liver disease, DIC, TTP |
10 -15 ml/kg increases factor levels 20 - 30% |
ABO compatible No Rh compatibility or X- match required |
Conditons responsive to volume replacement |
Frozen 1 year |
-30 o C or lower use preferably within 6 hrs after thawing at 37 o C |
Cryopre- cipitate |
10 - 25 ml |
Haemophilia A, Von Willebrand's disease, Hypofibrino- genemia, F XIII deficiency |
Factor VIII - 1 unit/kg increases level by 2% |
No ABO, Rh or X- match required |
Conditions not deficient in contained factors |
Frozen - 1 year |
-30 o C or lower use preferably within 6 hrs after thawing at 37 o C |
Cryopoor Plasma |
175 - 230 ml Albumin approx 8 gm. |
Multiple coagulation factor deficiency, Massive transfusion, Liver disease, DIC |
10 - 15 ml/kg increases factor levels 20 - 30% |
ABO compatible, no Rh compatibility or X- match required |
Conditions responsive to volume replacement |
Frozen - 1 year |
-30 o C or lower use preferably within 6 hrs after thawing at 37 o C |
Platelets Random donor (RDP) |
> 0.5 X 10 10 platelets from 450 ml of blood 45 - 65 mL |
Bleeding from throbocyto- penia, Functional defect of platelets |
Increases platelet count by 5000 to 10000µ/L per unit |
Preferably group compatible. However, non group specific platelets can be given |
Plasma coagulation factor deficit, TTP, HUS, ITP except in life saving situations |
5 days (special bags) |
20 o C - 24 o C with continuous agitation |
Platelets Single Donor (SDP) |
> 3 X 10 11 platelets 200 - 450 ml |
Best mode to correct throbocyto- penia by reducing refractori- ness |
Increases platelet count by 30 to 60000µ/L per unit |
ABO and Rh compatible HLA matched when indicated |
Plasma coagulation factor deficit, TTP, HUS, ITP except in life saving situations |
5 days (closed system) |
20 o C - 24 o C with continuous agitation |