Component: Red cells in additive solution
Description: 300 - 350 ml of RBCs in additive solution collected from 450 ml of whole blood
Indications: Sympto- matic anaemia acute or chronic for restoration of O 2 carrying capacity
Dosage Effect: 1 unit RBC increases Hct 3%, increases Hb by 1gm% (approx.)
Special Conside - rations: Must be ABO & Rh compatible and X- match compatible
Not indicated for: 1. Deficiency anaemias treatable pharmaco- logically 2. Coagula- tion factor deficiencies
Shelf life: 42 days
Storage conditions: 2 o C - 6 o C
Component: Washed RBCs
Description: 300 - 350 ml red cells washed in NS thrice under Laminar air flow
Indications: Sympto- matic anaemia with Plasma protein antibodies, IgA Ab.s, PNH, H/O febrile reactions
Dosage Effect: 1 unit RBC increases Hct 3%, increases Hb by 1gm% (approx.)
Special Conside - rations: Must be ABO & Rh compatible and X- match compatible
Not indicated for: 1. Deficiency anaemias treatable pharmaco- logically 2. Coagula- tion factor deficiencies
Shelf life: 24 hrs, however, to be consumed preferably in 6 hrs
Storage conditions: 2 o C - 6 o C
Component: Fresh frozen Plasma
Description: 200 - 250 ml, prepared within 6 hrs of whole blood collection preserving all clotting factors including labile factors (V & VIII)
Indications: Multiple coagulation factor deficiency, Massive transfusion, Liver disease, DIC, TTP
Dosage Effect: 10 -15 ml/kg increases factor levels 20 - 30%
Special Conside - rations: ABO compatible No Rh compatibility or X- match required
Not indicated for: Conditons responsive to volume replacement
Shelf life: Frozen 1 year
Storage conditions: -30 o C or lower use preferably within 6 hrs after thawing at 37 o C
Component: Cryopre - cipitate
Description: 10 - 25 ml
Indications: Haemophilia A, Von Willebrand's disease, Hypofibrino- genemia, F XIII deficiency
Dosage Effect: Factor VIII - 1 unit/kg increases level by 2%
Special Conside - rations: No ABO, Rh or X- match required
Not indicated for: Conditions not deficient in contained factors
Shelf life: Frozen - 1 year
Storage conditions: -30 o C or lower use preferably within 6 hrs after thawing at 37 o C
Component: Cryopoor Plasma
Description: 175 - 230 ml Albumin approx 8 gm.
Indications: Multiple coagulation factor deficiency, Massive transfusion, Liver disease, DIC
Dosage Effect: 10 - 15 ml/kg increases factor levels 20 - 30%
Special Conside - rations: ABO compatible, no Rh compatibility or X- match required
Not indicated for: Conditions responsive to volume replacement
Shelf life: Frozen - 1 year
Storage conditions: -30 o C or lower use preferably within 6 hrs after thawing at 37 o C
Component: Platelets Random donor (RDP)
Description: > 0.5 X 10 10 platelets from 450 ml of blood 45 - 65 mL
Indications: Bleeding from throbocyto- penia, Functional defect of platelets
Dosage Effect: Increases platelet count by 5000 to 10000µ/L per unit
Special Conside - rations: Preferably group compatible. However, non group specific platelets can be given
Not indicated for: Plasma coagulation factor deficit, TTP, HUS, ITP except in life saving situations
Shelf life: 5 days (special bags)
Storage conditions: 20 o C - 24 o C with continuous agitation
Component: Platelets Single Donor (SDP)
Description: > 3 X 10 11 platelets 200 - 450 ml
Indications: Best mode to correct throbocyto- penia by reducing refractori- ness
Dosage Effect: Increases platelet count by 30 to 60000µ/L per unit
Special Conside - rations: ABO and Rh compatible HLA matched when indicated
Not indicated for: Plasma coagulation factor deficit, TTP, HUS, ITP except in life saving situations
Shelf life: 5 days (closed system)
Storage conditions: 20 o C - 24 o C with continuous agitation